Table 1.
Patients, tumor, and systemic therapy characteristics
| IOERT boost arm | EBRT boost arm | p value | |
|---|---|---|---|
| Women in each arm | 125 (51%) | 110 (49%) | |
| Median age (range) | 56.3 years (29–75) | 56.2 years (34–75) | 0.96** |
| Menopausal status | 0.81* | ||
| Pre | 37 (30%) | 31 (28%) | |
| Post | 88 (70%) | 79 (72%) | |
| Disease laterality | 0.73* | ||
| Right breast | 54 (43%) | 50 (45%) | |
| Left breast | 71 (57%) | 60 (55%) | |
| Histology | 0.46* | ||
| IDC | 61 (49%) | 59 (54%) | |
| ILC | 17 (14%) | 11 (10%) | |
| DCIS | 3 (1.4%) | 3 (2.6%) | |
| IDC+DCIS | 32 (26%) | 24 (22%) | |
| Medullary | 6 (5%) | 4 (3.5%) | |
| ILC+ILCS | 5 (4%) | 5 (4.4%) | |
| Missing | 1 (0.6%) | 4 (3.5%) | |
| Pathologic T stage | 0.38* | ||
| pT1 | 96 (77%) | 79 (72%) | |
| pT2 | 28 (22%) | 22 (20%) | |
| pT3–pT4 | 1 (1%) | 1 (1%) | |
| Missing | 0 | 8 (7%) | |
| Pathologic N stage | 0.55* | ||
| pN0 | 82 (65%) | 68 (62%) | |
| pN1 | 38 (30%) | 32 (29%) | |
| pN2 | 2 (2.1%) | 1 (1%) | |
| pN3 | 1 (0.8%) | 1 (1%) | |
| Missing | 2 (2.1%) | 8 (7%) | |
| Adjuvant chemotherapy | 0.61* | ||
| Yes | 37 (30%) | 36 (33%) | |
| Not | 85 (68%) | 64 (58%) | |
| Missing | 3 (2%) | 10 (9%) | |
| Hormone therapy | 0.66* | ||
| Yes | 105 (84%) | 90 (81%) | |
| Not | 19 (15%) | 12 (11%) | |
| Missing | 1 (1%) | 8 (8%) | |
Abbreviations: IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; DCIS, ductal carcinoma in situ
**Mann-Whitney test
*Chi-square test