Table 3.
Study demographics
| Year | Author last name | Location | Population | Study design | Outcomes measured | Included in meta-analysis |
|---|---|---|---|---|---|---|
| 1996 | Schectman [34] | United States | Adult | RCT | LDL-C, Statin Adherence | ✓ |
| 1997 | Bogden [65] | United States | Adult | RCT | LDL-C | ✓ |
| 2000 | Nordmann [37] | Switzerland | Adult | RCT | Statin Prescribing | ✓ |
| 2000 | Nguyen [38] | France | Adult | RCT | LDL-C | ✓ |
| 2000 | Faulkner [71] | United States | Adult and Child | RCT | LDL-C | ✓ |
| 2005 | Rachmani [36] | Israel | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2006 | Lester [41] | United States | Adult | RCT | LDL-C | ✓ |
| 2006 | Lee [78] | United States | Adult | RCT | LDL-C | ✓ |
| 2007 | Khanal [77] | United States | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2008 | Riesen [35] | Switzerland | Adult | RCT | LDL-C | ✓ |
| 2009 | Stacy [31] | United States | Adult | RCT | Statin Adherence | ✓ |
| 2009 | Willich [89] | Germany | Adult | RCT | LDL-C | ✓ |
| 2009 | McAlister [101] | Canada | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2010 | Webster [23] | Australia | Adult | RCT | LDL-C | ✓ |
| 2010 | Villeneuve [103] | Canada | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2012 | Nieuwkerk [86] | Netherlands | Adult | RCT | LDL-C | ✓ |
| 2013 | Zamora [12] | Spain | Adult | RCT | LDL-C | ✓ |
| 2013 | Kooy [42] | Netherlands | Adult | RCT | Statin Adherence | ✓ |
| 2013 | Kardas [43] | Poland | Adult | RCT | Statin Adherence | ✓ |
| 2013 | Goswami [72] | United States | Adult | RCT | Statin Adherence | ✓ |
| 2014 | McAlister [83] | Canada | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2014 | Lowrie [100] | United Kingdom | Adult | RCT | Statin Prescribing | ✓ |
| 2015 | Mols [54] | Denmark | Adult | RCT | LDL-C | ✓ |
| 2015 | Asch [13] | United States | Adult | RCT | LDL-C | ✓ |
| 2015 | Patel [82] | Australia | Adult | RCT | LDL-C | ✓ |
| 2016 | Jakobsson [44] | Sweden | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 2016 | Damush [79] | United States | Adult | RCT | Statin Adherence | ✓ |
| 2018 | Choudhry [76] | United States | Adult | RCT | LDL-C, Statin Adherence | ✓ |
| 2018 | Mehrpooya [80] | Iran | Adult | RCT | LDL-C | ✓ |
| 2018 | Martinez [81] | Spain | Adult | RCT | LDL-C | ✓ |
| 2018 | Osborn [104] | United Kingdom | Adult | RCT | LDL-C, Statin Prescribing | ✓ |
| 1996 | Lindholm [39] | Sweden | Adult | RCT | LDL-C | |
| 2003 | Sebregts [99] | Netherlands | Adult and Child | RCT | LDL-C | |
| 2007 | Choe [95] | United States | Adult | RCT | LDL-C, Statin Adherence | |
| 2008 | Hung [90] | Taiwan | Adult | RCT | LDL-C, Statin Prescribing | |
| 2010 | Bhattacharyya [62] | Canada | Adult | RCT | LDL-C, Statin Prescribing | |
| 2013 | Dresser [55] | Canada | Adult | RCT | LDL-C | |
| 2013 | Brath [60] | Austria | Adult | RCT | LDL-C, Statin Adherence | |
| 2013 | Derose [85] | United States | Adult | RCT | Statin Adherence | |
| 2005 | Straka [28] | United States | Adult | Nonrandomized Clinical Trial | LDL-C | |
| 2005 | Paulos [105] | Chile | Adult | RCT | LDL-C, Statin Adherence | |
| 2006 | Vrijens [24] | Belgium | Adult | RCT | Statin Adherence | |
| 2015 | Persell [102] | United States | Adult | RCT | LDL-C, Statin Prescribing | |
| 2017 | Bosworth [61] | United States | Adult | RCT | LDL-C, Statin Adherence | |
| 2018 | Etxeberria [53] | Spain | Adult and Child | RCT | Statin Prescribing | |
| 1995 | Shaffer [94] | United States | Adult | Observational | LDL-C | |
| 1997 | Shibley [32] | United States | Adult | Observational | LDL-C | |
| 1999 | Schwed [33] | Switzerland | Adult | Observational | LDL-C, Statin Adherence | |
| 2000 | Robinson [92] | United States | Adult | Observational | LDL-C, Statin Prescribing | |
| 2000 | Birtcher [93] | United States | Adult | Observational | Statin Prescribing | |
| 2001 | Ford [52] | United Kingdom | Adult | Observational | Statin Prescribing | |
| 2002 | Viola [25] | United States | Adult | Observational | LDL-C, Statin Prescribing | |
| 2002 | Geber [50] | United States | Adult | Observational | LDL-C | |
| 2002 | Gavish [51] | Israel | Adult | Observational | LDL-C, Statin Adherence | |
| 2002 | Hilleman [70] | United States | Adult | Observational | LDL-C; Statin Prescribing | |
| 2003 | Truppo [27] | United States | Adult | Observational | LDL-C; Statin Adherence | |
| 2003 | Ryan [98] | United States | Adult | Observational | LDL-C; Statin Prescribing | |
| 2004 | Hilleman [45] | United States | Adult and Child | Observational | LDL-C | |
| 2004 | de Velasco [56] | Spain | Adult | Observational | LDL-C, Statin Prescribing | |
| 2004 | Lappé [69] | United States | Adult | Observational | Statin Prescribing | |
| 2005 | Harats [47] | Israel | Adult | Observational | LDL-C | |
| 2005 | Bassa [63] | Spain | Adult | Observational | LDL-C | |
| 2005 | Brady [91] | United Kingdom | Adult | Observational | Statin Prescribing | |
| 2005 | McLeod [96] | United Kingdom | Adult | Observational | Statin Adherence | |
| 2005 | Rabinowitz [97] | Israel | Adult | Observational | LDL-C | |
| 2006 | de Lusignan [57] | United Kingdom | Adult and Child | Observational | Statin Prescribing | |
| 2006 | Rehring [66] | United States | Adult | Observational | LDL-C | |
| 2007 | Goldberg [48] | United States | Adult | Observational | LDL-C | |
| 2008 | Stockl [29] | United States | Adult | Observational | Statin Prescribing, Statin Adherence | |
| 2008 | Hatfield [67] | United Kingdom | Adult | Observational | LDL-C, Statin Adherence | |
| 2008 | Coodley [88] | United States | Both | Observational | LDL-C | |
| 2009 | Stephenson [30] | United States | Adult and Child | Observational | LDL-C | |
| 2009 | Lima [40] | Brazil | Adult | Observational | LDL-C | |
| 2009 | Casebeer [59] | United States | Adult | Observational | Statin Adherence | |
| 2010 | Chen [75] | Taiwan | Adult | Observational | LDL-C | |
| 2011 | Gitt [49] | Germany | Adult | Observational | LDL-C | |
| 2011 | Chung [58] | Hong Kong | Adult | Observational | LDL-C | |
| 2011 | Schmittdiel [87] | United States | Adult | Observational | LDL-C | |
| 2012 | Aziz [68] | United States | Adult | Observational | LDL-C, Statin Prescribing | |
| 2012 | Farley [74] | United States | Adult | Observational | Statin Adherence | |
| 2014 | Clark [73] | United States | Adult and Child | Observational | Statin Adherence | |
| 2014 | Shoulders [84] | United States | Adult | Observational | LDL-C, Statin Prescribing | |
| 2015 | Vinker [26] | Israel | Adult | Observational | LDL-C, Statin Prescribing | |
| 2016 | Harrison [46] | United States | Adult | Observational | LDL-C, Statin Adherence | |
| 2017 | Andrews [64] | United States | Adult | Observational | Statin Adherence | |
| 2018 | Weng [22] | United Kingdom | Adult | Observational | LDL-C, Statin Prescribing |