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. 2021 Apr 13;21:192. doi: 10.1186/s12903-021-01552-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — (a) A sample of group III (Positive control) after one week showing the furcation defect filled with granulation tissue, no calcific bridge formation (yellow arrow), irregular silhouette of interradicular bone at the granulation tissue interface (blue arrows) and distorted thin discontinuous trabeculae (thin black arrows). (b) A higher magnification of the same sample in Fig. 3a showing absence of prominent calcification at the furcation perforation zone and many inflammatory cells scattered among collagen fibers (red circle) [H&E, X4 (a) and X40 (b)]