Table 5.
Association of body composition with fibrosis (≥ Stage 1) by multivariate analysis
Index | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
OR (95 % CI) | P-value | OR (95 % CI) | P-value | OR (95 % CI) | P-value | |
Muscle mass, kg | 0.97 (0.84–1.15) | 0.79a | 0.9 (0.77–1.05) | 0.18a | 0.92 (0.79–1.07) | 0.28a |
Fat mass, kg | 1.09 (1.02–1.18) | 0.02b | 1.09 (1.02–1.18) | 0.01b | 1.1 (1.02–1.18) | 0.01b |
BFMI, kg/m2 | 1.25 (1.03–1.55) | 0.02c | 1.27 (1.06–1.55) | 0.02c | 1.27 (1.06–1.56) | 0.02c |
Visceral fat area, cm2 | 1.02 (1.002–1.04) | 0.03b | 1.02 (1.01–1.05) | < 0.01 b | 1.02 (1.01–1.05) | < 0.01b |
Waist-hip ratio | 2.97 × 105 (1.64–1.52 × 109) | 0.04c | 1.09 × 105 (5.21–4.38 × 109) | 0.02c | 9.31 × 104 (0.78–3.68 × 108) | 0.07c |
SMI/BFMI | 0.14 (0.02–0.63) | 0.02 | 0.13 (0.02–0.57) | < 0.01 | 0.12 (0.02–0.55) | < 0.01 |
Model 1 was adjusted for age (years) of patient and sex of patient, and alanine aminotransferase (U/L) and creatinine (µmol/L) levels, along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
Model 2 was adjusted for age (years) of patient, sex of patient, and hemoglobin A1c levels (%), along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
Model 3 was adjusted for age (years) of patient and sex of patient, and total cholesterol (mmol/L) and triglyceride levels (mmol/L), along with afat mass (kg), bmuscle mass (kg), and cmuscle mass/ht2 (kg/m2)
OR, odds ratio; CI, confidence interval; BFMI, body fat mass index; SMI, skeletal muscle index; ht2, height squared