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FDR and recall (TPR) on simulated data. a In the classical DEU context. b In the differential UTR usage context. The dashed line indicates a real False Discovery Rate (FDR) of 5%, and the dots indicate nominal FDRs of 10, 5 and 1%. diffUTR methods, in particular the diffSplice2 and DEXSeq methods, outperform alternative methods. In both contexts, our modifications to diffSplice significantly improve its performance
