Table 3.
Anemia-related laboratory findings in patients with RDEB
| ReferenceS | Population (N) | Mean (SD) hemoglobin (g/dL) | Mean (SD) reticulocytes (%) | Mean (SD) ferritin (µg/L) | Mean (SD) transferrin (mg/L) | Mean (SD) transferin saturation (%) | Mean (SD) iron (µg/L) |
|---|---|---|---|---|---|---|---|
| Reimer [55] | Children with RDEB (157) | 9.7 (2.23) | 17.8 (16.3) | 63.0 (140.8) | 241.7 (60.6) | 9.9 (8.85) | 27.6 (23.7) |
| Normal range (NA) | 12.55–16.55 | 4.8–16.4 | 22.5–275 | 200–360 | 16–45 | 26–151.5 | |
| Hwang [34] | Children with RDEB (NR) | 10.19 (3.08) | NR | NR | NR | NR | NR |
| Mellerio [62] | RDEB severe, 0–16 years (NR) | 10.84 (NR) | NR | NR | NR | NR | NR |
| RDEB severe, 17–25 years (NR) | 12.30 (NR) | NR | NR | NR | NR | NR | |
| RDEB severe, 26–35 years (NR) | 11.09 (NR) | NR | NR | NR | NR | NR | |
| RDEB severe, 36–45 years (NR) | 8.80 (NR) | NR | NR | NR | NR | NR | |
| RDEB severe, 46–55 years (NR) | 9.30 (NR) | NR | NR | NR | NR | NR |
NA, not applicable; NR, not reported; RDEB, recessive dystrophic epidermolysis bullosa