Table 4.

Spearman’s correlation coefficients (r_s) between periodontal parameters, salivary cytokines and selected factors analyzed in the PCOS group (n = 31) and the control group (n = 28)

	N	GI		BOP%		PD		IL-1β (pg/ml)		IL-6 (pg/ml)		TNF-α (pg/ml)
		rs	p	rs	P	rs	p	rs	p	rs	p	rs	p
PI	31	0.61	0.0003*	0.60	0.0004*	0.17	0.3512	− 0.07	0.6947	0.07	0.7259	0.07	0.7153
	28	0.66	0.0002*	0.79	0.0000*	0.26	0.1733	− 0.35	0.0665	0.07	0.7277	− 0,10	0.5970
BMI	31	0.14	0.4101	0.26	0.1568	0.02	0.9029	− 0.17	0.3571	0.07	0.6964	0.18	0.3452
	28	0.36	0.0604	0.40	0.0368*	0.37	0.0497*	− 0.05	0.8151	− 0.17	0.3761	0.07	0.7333
Estradiol (pg/ml)	31	− 0.04	0.8202	0.05	0.7719	0.21	0.2492	− 0.24	0.1903	0.07	0.6980	0.05	0.7894
TT (ng/dl)	31	− 0.34	0.0622	− 0.27	0.1422	− 0.22	0.2417	0.08	0.6683	0.37	0.0400*	0.20	0.2891
FAI	31	− 0.20	0.2783	− 0.11	0.5495	− 0.18	0.3276	0.04	0.8403	0.32	0.0836	0.36	0.0491*
SHBG (nmol/l)	31	− 0.02	0.9164	− 0.15	0.4241	− 0.03	0.8560	− 0.02	0.9117	− 0.15	0.4308	− 0.15	0.4193
DHEA-S (µmol/l)	31	− 0.05	0.7884	− 0.15	0.4165	− 0.17	0.3561	0.33	0.0675	0.06	0.7482	0.26	0.1510
Cortisol (morning sample) (nmol/l)	31	0.14	0.4382	0.18	0.3333	0.08	0.6837	0.12	0.5308	0.30	0.1050	− 0.08	0.6852
Cortisol/DHEA-S	31	0.11	0.5609	0.30	0.0999	0.22	0.2265	− 0.09	0.6303	0.18	0.3397	− 0.18	0.3412
Fasting glucose (mg/dl)	31	− 0.04	0.8219	− 0.13	0.4844	− 0.27	0.1463	0.07	0.6979	0.05	0.7852	0.15	0.4104
Fasting insulin (mU/ml)	31	0.23	0.2044	0.36	0.0469*	0.21	0.2669	0.08	0.6780	0.24	0.2022	0.01	0.9716
HOMA-IR	31	0.28	0.1301	0.48	0.0068*	0.24	0.1866	0.11	0.5535	0.14	0.4456	0.04	0.8202
TC (mg/dl)	31	− 0.31	0.0869	− 0.06	0.7325	− 0.21	0.2683	0.09	0.6450	0.25	0.1815	0.06	0.7686
LDL-C (mg/dl)	31	− 0.34	0.0578	− 0.10	0.5803	− 0.26	0.1580	− 0.04	0.8361	0.29	0.1085	0.05	0.7960
HDL-C (mg/dl)	31	− 0.02	0.9027	− 0.05	0.7925	0.18	0.3306	0.29	0.1200	− 0.20	0.2831	− 0.14	0.4533
TG (mg/dl)	31	− 0.03	0.8745	0.16	0.3967	− 0.15	0.4183	0.27	0.1436	0.31	0.0857	0.14	0.4475
Salivary testosterone (pg/ml)	31	− 0.44	0.0138*	− 0.37	0.0424*	− 0.06	0.7338	0.00	0.9888	0.33	0.0740	0.07	0.7019
	28	0.11	0.5725	− 0.05	0.8197	− 0.16	0.4145	0.01	0.9526	0.01	0.9438	0.41	0.0312*
TNF-α (pg/ml)	31	− 0.26	0.1664	− 0.13	0.4909	− 0.20	0.2910	− 0.15	0.4318	0.54	0.0018*	N.A	N.A
	28	0.35	0.0668	0.10	0.6007	0.00	1.0000	0.19	0.3240	0.12	0.5471	N.A	N.A
IL-6 (pg/ml)	31	− 0.24	0.1976	− 0.07	0.7172	− 0.10	0.5991	0.05	0.3935	N.A	N.A	–	–
	28	0.01	0.9801	− 0.06	0.7510	− 0.20	0.3046	0.25	0.2006	N.A	N.A	–	–
IL-1β (pg/ml)	31	0.06	0.7342	0.08	0.6759	0.06	0.7680	N.A	N.A	–	–	–	–
	28	− 0.14	0.4634	− 0.26	0.2551	0.01	0.9643	N.A	N.A	–	–	–	–

TT, total testosterone; FAI, free androgen index; SHGB, sex hormone-binding globulin; DHEA-S, dehydroepiandrosterone sulfate; HOMA-IR, Homeostatic Model Assessment of Insulin Resistance; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides; TNF-α, tumor necrosis factor α; IL-6, interleukin 6; IL-1β, interleukin 1β; N.A., not applicable

^*Statistically significant correlations