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. 2021 Apr 14;36(6):1841–1843. doi: 10.1007/s11606-021-06759-9

Table 1.

Positive Screening for Anxiety Was Defined as a Score of 3 or Higher on a Modified General Anxiety Disorder-2 (GAD-2) Questionnaire. DiD Difference in Difference. Positive Screening for Depression Was Defined as a Score of 3 or Higher on a Modified Patient Health Questionaire-2 (PHQ-2). *n=939,936. COVID Per-Capita Infection Rate Was Calculated for Each State by Taking the Center for Disease Control’s 7-day Average of New COVID Cases as of July 21st (the Last Day of the Study Period) Divided by the State’s 2019 Population. Survey Respondents Were Then Divided into Quintiles Based on These Infection Rates

Prevalence of positive screening for anxiety or depression
Unadjusted results Adjusted results
April 23–May 5, 2020 July 16–July 21, 2020 Absolute change (95% CI) p value DiD estimate (95% CI) p
All respondents n=988,349
35.9 40.9 5.0 (4.6, 5.4) <0.001 NA NA
Sex
Male 31.0 37.0 6.1 (5.7,6.5) <0.001 Reference
Female 40.7 44.6 4.0 (3.4,4.5) <0.001 −2.1 (−2.2, −2.0) <0.001
Age
18–44 41.9 49.3 7.5 (7.4,7.5) <0.001 3.6 (3.6,3.7) <0.001
45–65 35.7 39.5 3.8 (3.8,3.9) 0.001 Reference
65+ 23.6 25.4 1.8 (−0.30,3.9) 0.09 −2.0 (−4.0,.1) 0.06
Education
<HS 45.4 47.3 2.0 (−0.40,4.3) 0.10 −2.9 (−5.4, −.38) 0.02
HS 36.7 42.2 5.5 (4.0,7.1) <.001 .6 (−.68 , 2.0) 0.34
Some college 34.5 39.4 4.9 (4.7,5.1) <.001 Reference
Race

Non-Hispanic

White

33.6 38.8 5.3 (4.5,6.1) <0.001 Reference

Non-Hispanic

Black

38.9 42.6 3.8 (3.2,4.4) <0.001 −1.5 (−2.9, −.10) 0.04

Non-Hispanic

Asian

31.9 40.3 8.4 (2.5,14.3) 0.006 3.1 (−2.0,8.2) 0.23

Non-Hispanic

Other

43.9 48.8 4.9 (3.5,6.3) <0.001 −.4 (−.98,.17) 0.16
Hispanic 42.7 46.3 3.6 (1.4,5.8) 0.002 −1.7 (−4.7,1.4) 0.28
2019 family income *
<$25K 51.0 54.1 3.1 (0.70,5.4) 0.01 −1.0 (−3.9, 1.9) 0.52
$25K–50K 38.9 47.1 8.2 (6.4,10.1) <0.001 4.2 (1.8,6.6) 0.001
$50K–100K 34.3 37.7 3.4 (2.8,4.0) <0.001 −0.62 (−0.65, −0.59) <0.001
$100K + 26.8 30.8 4.0 (3.5,4.6) <0.001 Reference
COVID infection rate in state
Lowest quintile 38.4 37.7 −0.7 (−1.4, −0.02) 0.04 Reference
Quintile 2 35.3 41.1 5.8 (5.2,6.4) <.001 6.5 (6.4,6.6) <0.001
Quintile 3 35.1 41.0 5.9 (4.2,7.6) <.001 6.6 (4.2,9.0) <0.001
Quintile 4 34.8 44.2 9.4 (9.4,9.5) <.001 10.1 (9.4,10.9) <0.001
Highest quintile 35.8 42.2 6.4 (5.2,7.6) <.001 7.1 (5.2, 9.0) <0.001