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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: J Hepatol. 2020 Nov 24;74(4):850–859. doi: 10.1016/j.jhep.2020.11.023

Table 2.

Characteristics of HCC among cases

Cases N (%)
Method of HCC diagnosis*
Imaging (CT/MRI) 160(94.7)
Histology 79(46.7)
Treatment of HCC*
Liver transplantation 2(1.2)
Surgery (partial hepatectomy) 9(5.3)
Systemic chemotherapy (sorafenib) 72(42.6)
Trans-arterial chemoembolization 58(34.3)
Radiofrequency ablation 19(11.2)
Y-90 radioembolization 7(4.1)
Percutaneous ethanol injection 1(0.6)
Cryoablation 0(0.0)
Other Treatment 22(13.0)
Any one of the above treatments 118(69.8)
Stage of HCC at Diagnosis
Maximum dimension of largest tumor (cm), mean (SD) 6.4(4.4)
Number of tumors, mean (SD) 2.2(1.7)
Number of tumors (%)
1 86(57.0)
2–3 28(18.5)
≥4 37(24.5)
Size of largest tumor (%)
0–3 cm 32(18.9)
3 to <5 cm 41(24.3)
5 to <6 cm 8(4.7)
6 to <7 cm 10(5.9)
≥7 cm 78(46.2)
Within Milan Criteria (%) 70(34.4)
Beyond Milan Criteria (%) 117(65.6)
Vascular Invasion, % 47(27.8)
Metastasis, % 24(14.2)
HCC Contributed to patient’s death*
Metastatic HCC 58(34.3)
Multifocal HCC (>3 lesions) 70(41.4)
Local or vascular invasion by HCC 70(41.4)
Large Volume HCC (>6cm or AFP>1000) 124(73.4)
Death due to complications of HCC treatment 5(3.0)
*

The categories for “method of HCC diagnosis”, “treatment of HCC” and “HCC contributed to patienťs death” are NOT mutually exclusive.

Milan Criteria: One tumor <5 cm or 2–3 tumors each of which is < 3cm

Abbreviations: HCC – hepatocellular carcinoma, CT – computed tomography, MRI – magnetic resonance imaging, SD – standard deviation, AFP – alpha fetoprotein