Table 1.

Summary statistics for the hormonal activities of 46 indoor dust samples in luciferase reporter gene assays.

Assay end point	Abbreviation	Reference compound	Percentage detected	GM (GSD)	Median	Range among detected	Units
Peroxisome proliferator-activated receptor $\mathrm{\gamma }2$ antagonism	$\text{PPAR}\mathrm{\gamma }$	GW9662 (chemical)	100% (46 of 46)	0.554 (1.92)	0.580	0.150–2.90	$\mathrm{\mu }\mathrm{g}\text{-eq}/\mathrm{g}$
Estrogen receptor $\mathrm{\alpha }$ agonism	ER	$17\mathrm{\beta }\text{-estradiol}$ (natural hormone)	96% (44 of 46)	2.21 (2.38)	1.76	0.287–22.0	$\text{ng-eq}/\mathrm{g}$
Thyroid hormone receptor $\mathrm{\beta }$ antagonism	TR	Deoxynivalenol (mycotoxin)	89% (41 of 46)	68.7 (2.30)	80.8	12.8–370	$\mathrm{\mu }\mathrm{g}\text{-eq}/\mathrm{g}$
Androgen receptor antagonism	AR	Flutamide (medication)	87% (40 of 46)	105 (2.26)	104	27.5–434	$\mathrm{\mu }\mathrm{g}\text{-eq}/\mathrm{g}$
Thyroid hormone transport interference	TTR-${\mathrm{T}}_4$	Perfluorooctanoate (PFAS chemical)	98% (45 of 46)	104 (2.90)	141	15.2–626	$\mathrm{\mu }\mathrm{g}\text{-eq}/\mathrm{g}$

Note: Activities by sample can be found in Table S2 and Figure S2. AR, androgen receptor; ER, estrogen receptor; GM, geometric mean; GSD, geometric standard deviation; PFAS, per- and polyfluoroalkyl substances; $\text{PPAR}\mathrm{\gamma }2$, peroxisome proliferator-activated receptor; TR, transport protein; TTR-${\mathrm{T}}_4$, transthyretin–thyroxine.