Table 4.
Multivariable Cox regression of OS, EFS, and CIR in 183 patients
| Factor | OS | EFS | CIR | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| WBC × 10 9 /L | |||||||||
| <100 | Reference | Reference | Reference | ||||||
| ≥100 | 1.483 | 0.691-3.186 | .312 | 1.052 | 0.515-2.148 | .889 | 0.758 | 0.305-1.883 | .550 |
| FAB subtype | |||||||||
| M1/M2 | Reference | Reference | Reference | ||||||
| M4/M5 | 0.994 | 0.411-2.406 | .990 | 0.932 | 0.465-1.867 | .842 | 2.008 | 0.844-4.777 | .115 |
| Other | 2.118 | 0.800-5.612 | .131 | 1.586 | 0.715-3.519 | .256 | 1.158 | 0.354-3.793 | .808 |
| Definitive risk | |||||||||
| Low | Reference | Reference | Reference | ||||||
| Intermediate | 2.156 | 0.483-9.631 | .314 | 2.566 | 0.765-8.609 | .127 | 2.286 | 0.484-10.805 | .297 |
| High | 7.831 | 1.629-37.637 | .010 | 6.201 | 1.689-22.769 | .006 | 3.900 | 0.769-19.783 | .100 |
| HSCT | |||||||||
| No | Reference | Reference | Reference | ||||||
| Yes | 0.390 | 0.197-0.769 | .007 | 0.693 | 0.397-1.212 | .198 | 1.054 | 0.514-2.162 | .886 |
| Induction treatment | |||||||||
| SDC/SDC | Reference | Reference | — | Reference | |||||
| LDC/LDC | 1.387 | 0.674-2.857 | .375 | 1.439 | 0.788-2.628 | .236 | 1.630 | 0.801-3.317 | .178 |
| LDC/SDC | 1.141 | 0.368-3.542 | .819 | 1.115 | 0.437-2.843 | .820 | 0.738 | 0.214-2.545 | .630 |
HR, hazard ratio.