Table 3.
effect of subacute oral administration of QHGC extract on hematological parameters in SD rats
| Parameter | Group 1 (0 g/kg/day) | Group 2 (4.0 g/kg/day) | Group 3 (8.0 g/kg/day) | Group 4 (16.0 g/kg/day) |
|---|---|---|---|---|
| Male | ||||
| RBC (1012/mm3) | 8.39 ± 0.32 | 8.46 ± 0.39 | 8.67 ± 0.44 | 8.56 ± 0.27 |
| Hb (g/l) | 159.20 ± 7.84 | 158.50 ± 4.93 | 164.60 ± 7.38 | 165.90 ± 4.09 |
| HCT (%) | 46.39 ± 2.08 | 46.64 ± 2.31 | 47.15 ± 2.03 | 48.23 ± 1.45 |
| PLT (109/l) | 1289.50 ± 137.63 | 1271.10 ± 140.14 | 1365.90 ± 153.70 | 1272.70 ± 82.40 |
| MPV (fl) | 7.64 ± 0.36 | 8.06 ± 0.39 | 7.39 ± 0.20 | 7.78 ± 0.40 |
| MCV (fl) | 55.32 ± 2.16 | 55.14 ± 1.90 | 54.44 ± 1.28 | 56.42 ± 2.01 |
| MCH (pg) | 19.00 ± 0.74 | 18.73 ± 0.38 | 19.01 ± 0.46 | 19.39 ± 0.65 |
| MCHC (g/l) | 343.20 ± 4.37 | 340.20 ± 8.32 | 349.10 ± 4.77 | 344.10 ± 5.00 |
| WBC (109/l) | 7.02 ± 2.63 | 7.43 ± 5.24 | 9.63 ± 2.67 | 8.94 ± 2.10 |
| NEUT (%) | 15.93 ± 5.59 | 18.41 ± 7.55 | 13.09 ± 2.50 | 11.42 ± 3.70 |
| LYM (%) | 80.30 ± 5.21 | 78.52 ± 7.06 | 82.75 ± 2.68 | 84.55 ± 4.42 |
| MONO (%) | 3.30 ± 0.72 | 2.72 ± 1.26 | 3.74 ± 0.69 | 3.63 ± 1.00 |
| EOS (%) | 0.45 ± 0.42 | 0.33 ± 0.35 | 0.39 ± 0.20 | 0.37 ± 0.31 |
| NEUT(103/l) | 1.04 ± 0.35 | 1.15 ± 0.60 | 1.26 ± 0.46 | 0.98 ± 0.26 |
| LYM (109/l) | 5.70 ± 2.25 | 6.03 ± 4.50 | 7.97 ± 2.19 | 7.60 ± 1.95 |
| MONO (109/l) | 0.23 ± 0.10 | 0.22 ± 0.17 | 0.36 ± 0.13 | 0.32 ± 0.10 |
| EOS (109/l) | 0.04 ± 0.04 | 0.04 ± 0.06 | 0.03 ± 0.02 | 0.03 ± 0.03 |
| Female | ||||
| RBC (1012/mm3) | 8.77 ± 0.34 | 8.89 ± 0.55 | 8.62 ± 0.44 | 8.68 ± 0.37 |
| Hb (g/l) | 165.20 ± 5.57 | 166.00 ± 7.60 | 161.00 ± 6.04 | 163.60 ± 5.97 |
| HCT (%) | 47.49 ± 1.37 | 47.54 ± 1.77 | 46.80 ± 1.89 | 523.22 ± 1506.22 |
| PLT (109/l) | 1244.40 ± 102.35 | 1036.03 ± 398.56 | 1184.10 ± 126.19 | 1173.80 ± 127.38 |
| MPV (fl) | 7.56 ± 0.26 | 7.30 ± 0.27 | 7.73 ± 0.27 | 7.52 ± 0.24 |
| MCV (fl) | 54.21 ± 1.41 | 53.58 ± 2.17 | 54.30 ± 1.31 | 54.24 ± 2.73 |
| MCH (pg) | 18.85 ± 0.45 | 18.70 ± 0.53 | 18.67 ± 0.52 | 18.86 ± 0.77 |
| MCHC (g/l) | 347.70 ± 5.70 | 349.10 ± 5.36 | 344.30 ± 7.97 | 348.00 ± 5.14 |
| WBC (109/l) | 5.79 ± 2.31 | 7.98 ± 2.84 | 7.25 ± 3.37 | 6.80 ± 2.72 |
| NEUT (%) | 11.11 ± 6.61 | 6.54 ± 2.18 | 6.58 ± 3.24 | 7.74 ± 6.41 |
| LYM (%) | 85.30 ± 6.66 | 90.43 ± 2.74 | 89.69 ± 4.46 | 88.97 ± 7.08 |
| MONO (%) | 3.39 ± 0.78 | 2.63 ± 1.01 | 3.47 ± 1.74 | 3.06 ± 1.31 |
| EOS (%) | 0.20 ± 0.35 | 0.39 ± 0.47 | 0.19 ± 0.23 | 0.22 ± 0.37 |
| NEUT (103/l) | 0.59 ± 0.39 | 0.48 ± 0.13 | 0.39 ± 0.12 | 0.48 ± 0.29 |
| LYM (109/l) | 4.99 ± 2.11 | 7.25 ± 2.72 | 6.59 ± 3.28 | 6.09 ± 2.56 |
| MONO (109/l) | 0.20 ± 0.09 | 0.21 ± 0.12 | 0.24 ± 0.12 | 0.22 ± 0.15 |
| EOS (109/l) | 0.02 ± 0.03 | 0.03 ± 0.04 | 0.02 ± 0.03 | 0.02 ± 0.04 |
The data are presented as mean ± SD (n = 10). There was no significant difference.