Table 4.
effects of subacute doses of QHGC extract on biochemical parameters in male and female SD rats
| Subacute dose | ||||
|---|---|---|---|---|
| Parameter | Group 1 (0 g/kg/day) | Group 2 (4.0 g/kg/day) | Group 3 3 (8.0 g/kg/day) | Group 4 (16.0 g/kg/day) |
| Male | ||||
| ALB (g/dl) | 36.30 ± 1.52 | 36.86 ± 1.87 | 37.23 ± 1.62 | 36.60 ± 1.11 |
| ALP (U/l) | 179.87 ± 27.17 | 208.90 ± 39.05 | 208.01 ± 25.66 | 192.71 ± 30.34 |
| ALT (U/l) | 48.79 ± 7.48 | 52.69 ± 11.26 | 56.34 ± 10.77 | 50.08 ± 3.16 |
| AST (U/l) | 124.61 ± 42.24 | 117.31 ± 24.19 | 123.09 ± 30.79 | 117.07 ± 28.26 |
| CK (U/l) | 329.10 ± 119.69 | 296.26 ± 65.88 | 274.38 ± 69.94 | 352.58 ± 110.48 |
| BUN (mg/dl) | 4.22 ± 1.00 | 4.29 ± 0.83 | 4.84 ± 0.79 | 4.32 ± 0.63 |
| CRE (mg/dl) | 26.88 ± 2.00 | 27.00 ± 3.74 | 25.99 ± 3.15 | 26.86 ± 3.36 |
| GLU (mg/dl) | 8.11 ± 1.24 | 7.70 ± 0.86 | 8.27 ± 1.21 | 7.98 ± 0.93 |
| TC (mg/dl) | 1.86 ± 0.39 | 1.90 ± 0.29 | 1.99 ± 0.33 | 1.98 ± 0.48 |
| TG (mg/dl) | 1.64 ± 0.25 | 1.46 ± 0.17 | 1.73 ± 0.14 | 1.58 ± 0.14 |
| TP (g/dl) | 70.65 ± 3.28 | 72.06 ± 3.01 | 73.17 ± 3.25 | 72.09 ± 1.67 |
| K+ (mmol/l) | 2.47 ± 0.28 | 2.32 ± 0.23 | 2.36 ± 0.36 | 2.52 ± 0.26 |
| Na+ (mmol/l) | 107.43 ± 18.74 | 102.73 ± 1.34 | 105.03 ± 3.68 | 102.05 ± 0.74 |
| Cl-(mmol/l) | 108.00 ± 2.99 | 109.85 ± 2.63 | 112.78 ± 5.15 | 108.94 ± 0.96 |
| Ca2+ (mmol/l) | 2.17 ± 0.13 | 2.16 ± 0.09 | 2.23 ± 0.09 | 2.19 ± 0.06 |
| Female | ||||
| ALB (g/dl) | 43.15 ± 4.20 | 43.89 ± 2.41 | 43.42 ± 3.90 | 41.48 ± 2.90 |
| ALP (U/l) | 101.18 ± 36.43 | 103.34 ± 23.85 | 109.50 ± 49.75 | 111.52 ± 52.12 |
| ALT (U/l) | 42.10 ± 5.35 | 44.29 ± 13.15 | 34.95 ± 9.64 | 43.74 ± 13.41 |
| AST (U/l) | 97.13 ± 20.64 | 112.63 ± 25.13 | 105.49 ± 27.04 | 119.05 ± 37.48 |
| CK (U/l) | 216.64 ± 109.70 | 214.19 ± 90.46 | 272.07 ± 212.38 | 375.08 ± 299.69 |
| BUN (mg/dl) | 5.95 ± 2.39 | 6.33 ± 1.14 | 6.96 ± 2.26 | 6.15 ± 1.21 |
| CRE (mg/dl) | 34.32 ± 7.46 | 38.98 ± 8.59 | 38.94 ± 13.93 | 33.70 ± 4.94 |
| GLU (mg/dl) | 8.21 ± 1.55 | 7.52 ± 0.91 | 8.51 ± 1.04 | 8.78 ± 0.77 |
| TC (mg/dl) | 2.03 ± 0.52 | 2.19 ± 0.41 | 1.94 ± 0.29 | 2.25 ± 0.44 |
| TG (mg/dl) | 1.50 ± 0.20 | 1.41 ± 0.07 | 1.43 ± 0.20 | 1.54 ± 0.12 |
| TP (g/dl) | 81.93 ± 5.57 | 84.43 ± 3.27 | 84.60 ± 6.02 | 81.14 ± 5.44 |
| K+ (mmol/l) | 2.44 ± 0.32 | 2.25 ± 0.21 | 2.43 ± 0.23 | 2.44 ± 0.29 |
| Na+ (mmol/l) | 106.14 ± 4.45 | 110.98 ± 1.65 | 110.15 ± 5.74 | 110.39 ± 3.26 |
| Cl-(mmol/l) | 116.84 ± 3.68 | 119.11 ± 1.83 | 118.89 ± 3.56 | 119.87 ± 2.60 |
| Ca2+ (mmol/l) | 2.38 ± 0.11 | 2.43 ± 0.08 | 2.41 ± 0.14 | 2.38 ± 0.13 |
Data are presented as mean ± SD (n = 10). There were no significant differences between groups.