Table 2.
GAS inhibited Pb-induced oxidative stress in the kidneys of mice
| MDA (nM/mg prot) | SOD (U/mg prot) | GSH (U/mg prot) | GPx (U/mg prot) | |
|---|---|---|---|---|
| Control | 314.26 ± 12.71 | 232.64 ± 21.62 | 131.43 ± 23.18 | 112.82 ± 14.23 |
| Pb | 453.52 ± 21.07## | 150.18 ± 28.32## | 68.53 ± 12.32## | 86.73 ± 14.16## |
| Pb + GAS (50 mg/kg) | 426.18 ± 15.34** | 198.38 ± 15.26** | 88.42 ± 12.23** | 96.24 ± 21.04** |
| Pb + GAS (100 mg/kg) | 370.82 ± 21.03** | 225.17 ± 23.12** | 121.85 ± 13.86** | 108.72 ± 13.21** |
| GAS (100 mg/kg) | 312.37 ± 11.62** | 234.67 ± 20.43** | 132.63 ± 14.64** | 113.06 ± 12.59** |
One-way ANOVA was used for comparisons of multiple group means followed by post hoc testing. Data are expressed as mean ± S.E.M. (n = 7). ##P < 0.05, compared with the control group; **P < 0.05, vs. Pb-treated group.