Figure 11.

binding of piperine with Bcl-2. (a) Ribbon diagram of Bcl-2 with piperine in the active site. Piperine has been shown in yellow color and stick representation. Interacting residues are shown in hot pink color as sticks. (b) Surface diagram of Bcl-2 protein with piperine (yellow color and stick representation) showing the active site pocket. (c) Interaction of piperine with the critical residues of Bcl-2. Interacting residues are shown in hot pink color as sticks. Piperine is shown in yellow color as sticks. Hydrogen bonds are labeled and shown as black dash lines. (d) 2D interaction diagram of piperine with Bcl-2.