Figure 6.

effect of black pepper methanol extract and piperine (IC₂₅ and IC₅₀, 48 h) on apoptosis in K-562 cells. Representative FACS analysis of the cells performed using Annexin V as a marker. Bar graph indicating the sum of cells in the UR and LR quadrants of respective treatment groups. Each bar indicates mean ± SEM of three independent experiments and expressed as percent apoptosis rate. * represents P < 0.05 as compared with the control group. UL, upper left; UR, upper right; LL, lower left; LR, lower right; BP-M, black pepper methanol extract; PIP, piperine; IC₂₅ and IC₅₀, IC₂₅ and IC₅₀ equivalent concentrations, respectively.