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. 2021 Feb 13;10(2):345–353. doi: 10.1093/toxres/tfab002

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Representative photomicrographs of experimental rat kidney. Control rats showed normal kidney morphology. Kidney of rats treated with TAM alone showing glomerulonecrosis and tubular desquamation (green arrow), and presence of inflammatory cells (black notched arrow). The kidney of rats co-treated with CGA + TAM dose-dependently abated TAM-mediated injuries in the kidney with visible improvement in the kidney cyto-architecture at CGA1, and histological features were somewhat similar to controls at higher CGA dose (CGA2), except with mild disseminated congestion in the kidney. H and E stained, magnification: top row ×400; bottom row ×100.