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Effect of CGA on the levels of RONS and LPO and the activity of XO in the liver and kidney of rats treated with TAM for 2 weeks. Tamoxifen -TAM: 50 mg/kg; Chlorogenic acid -CGA: 25 and 50 mg/kg; TAM + CGA1, (50 + 25) mg/kg; TAM + CGA2, (50 + 50) mg/kg. Each bar represents mean ± SD of 10 rats. *P < 0.05 versus control; #P < 0.05 versus TAM only. SD: standard deviation; RONS: reactive oxygen/nitrogen species; LPO: lipid peroxidation; XO: xanthine oxidase.
