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. 2021 Mar 23;10(2):272–276. doi: 10.1093/toxres/tfab014

Table 2.

Effect of DIOB on biochemical indices in mice

Biochemical indices Control 10 mg/kg 30 mg/kg 60 mg/kg
ALT (IU/l) 35.7 ± 4.1 59.3 ± 4.3** 53.7 ± 19.3** 52.3 ± 5.0**
TP (g/l) 57.5 ± 2.4 55.9 ± 3.1 61.9 ± 4.9 55.0 ± 3.3
CREA (μmol/l) 18.7 ± 1.9 24.9 ± 1.7 19.0 ± 8.0 21.0 ± 5.6
CHOl (mmol/l) 2.4 ± 0.1 1.3 ± 0.1* 2.9 ± 1.2 1.9 ± 0.3
BUN (mmol/l) 3.4 ± 0.1 4.7 ± 0.1* 6.9 ± 1.1** 5.0 ± 0.2*
GLU (mmol/l) 14.1 ± 0.8 4.5 ± 0.2** 4.5 ± 1.2** 2.9 ± 0.3**
TG (mmol/l) 1.5 ± 0.0 0.5 ± 0.1** 1.7 ± 0.5 0.3 ± 0.0**
CHE (U/l) 197.8 ± 33.0 223.8 ± 40.3 5562.1 ± 1733.1** 263.8 ± 15.2*

Data are the mean ± SEM (n = 15). Statistical analysis was performed by one-way Anova with Tukey’s test for comparisons between groups.

* P < 0.05.

* * P < 0.01.