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Scratching and hair loss induced by gefitinib. The scratch bouts of C57BL/6 mice (A)and FVB/N mice (B) were recorded at 35th day, treated without (saline) or with gefitinib (37.5 mg/kg, 75 mg/kg and 150 mg/kg of body weight, n≥4, apart from the FVB/N in 150 mg/kg after 35 days, n=2). Mice hair weight per unit area were counted after mice sacrificed, n=3 (C, D). Data were analyzed using One-way ANOVA and presented as the mean ± SEM. Compared with control, **p < 0.01.
