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TEM images of A549 cells after treatment with 50 µg/ml ZnO (upper panel, left) or 50 µg/ml TiO2 (upper panel, right) during 3 h. Black arrows indicate small agglomerations of NPs inside vesicles in the cells. Cells treated with genistein (0, 2 mM) for 30 min at 37 °C and exposed to TiO2 NPs for 3 h (lower panel, left) Cells treated with amiloride (1 mM) for 30 min at 37 °C and exposed to TiO2 NPs for 3 h (lower panel, right).
