Table 3.
Demographic details and clinical characteristics of culture-positive Burkholderia pseudomallei cases from pyogenic lesions (n = 34)
| Demographic profile | No. of patients (%) (n = 34) |
|---|---|
| Age-group (years) | |
| ≤ 18 | 5 (14.7) |
| > 18–60 | 26 (76.5) |
| > 60 | 3 (8.8) |
| Mean ± SD | |
| 39.1 ± 16.8 | – |
| Median | |
| 39.5 | – |
| Range | |
| 7–71 | – |
| Gender | |
| Male | 24 (70.6) |
| Female | 10 (29.4) |
| Occupation | |
| Outdoor | |
| Laborer | 12 (35.3) |
| Military personnel | 2 (5.9) |
| Driver | 2 (5.9) |
| Farmers | 2 (5.9) |
| Indoor | |
| Homemaker | 8 (23.5) |
| Student | 5 (14.7) |
| Office worker | 2 (5.9) |
| Teacher | 1 (2.9) |
| Seasonal distribution | |
| Monsoon (June–September) | 20 (58.8) |
| Autumn (October–November) | 7 (20.6) |
| Winter (December–February) | 4 (11.8) |
| Summer (March–May) | 3 (8.8) |
| Clinical presentation | |
| Head and neck | 12 (35.3) |
| Musculoskeletal lesions | 11 (32.3) |
| Deep organ abscess | 8 (23.5) |
| Abdominal wall abscess | 1 (2.9) |
| Others* | 2 (6) |
| Risk factors/comorbid conditions† | |
| DM | 10 (29.4) |
| DM and alcoholism | 5 (14.7) |
| Alcoholism | 4 (11.7) |
| Hematological disorders‡ | 3 (8.8) |
| No apparent risk factor | 12 (35.3) |
| Treatment undertaken | 33 (97.1)§ |
| Initial therapy | |
| Ceftazidime | 28 (82.4) |
| Meropenem | 4 (11.7) |
| Imipenem | 1 (2.9) |
| Eradication therapy | |
| Co-trimoxazole | 30 (88.2) |
| Doxycycline | 2 (5.9) |
| Amoxicillin–clavulanate | 1 (2.9) |
| Outcome | |
| Treated | 31 (91.2) |
| Relapse | 2 (5.9) |
| Death | 1 (2.9) |
DM = diabetes mellitus.
*
Includes one case each of mediastinal lymph node aspirate and pleural empyema.
†
P < 0.05 (significant) for occurrence of diabetes between melioidosis and non-melioidosis patients by Chi-square test.
‡
Includes anemia, thalassemia, and sickle cell disease.
§
One patient died before initiation of treatment.