Table 4.
Minimum inhibitory concentration characteristics of Burkholderia pseudomallei (n = 34) to various antimicrobials
| Antibiotic | No. of isolates with MIC (µg/mL) | MIC (µg/mL) | % S | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.19 | 0.25 | 0.38 | 0.5 | 0.75 | 1 | 1.5 | 2 | 3 | 4 | 6 | 16 | Range | MIC50 | MIC90 | ||
| AMC | – | – | – | – | – | 1 | 4 | 4 | 17 | 2 | 5 | 1 | 1–16 | 3 | 6 | 97.1 |
| CAZ | – | – | – | – | – | – | 3 | 9 | 13 | 8 | 1 | – | 1.5–6 | 3 | 4 | 100 |
| DO | – | – | – | 3 | 8 | 10 | 6 | 5 | 1 | 1 | – | – | 0.5–4 | 1 | 2 | 100 |
| IPM | 4 | 12 | 7 | 6 | 1 | – | 1 | 1 | 2 | – | – | – | 0.19–3 | 0.38 | 1.5 | 100 |
| TMS | 2 | 5 | 2 | 2 | 7 | 10 | 4 | 2 | – | – | – | – | 0.19–2 | 0.75 | 1.5 | 100 |
AMC = amoxicillin–clavulanic acid; CAZ = ceftazidime; DO = doxycycline; IPM = imipenem; MIC = minimum inhibitory concentration; TMS = trimethoprim–sulfamethoxazole; S = susceptible.