Table 4.
Predictors of fatal severe fever with thrombocytopenia syndrome cases
| Variable | Nonfatal case (n = 189), n (%) | Fatal case (n = 19), n (%) | Crude OR (95% CI) | Adjusted OR (95% CI) |
|---|---|---|---|---|
| MOF | ||||
| No | 128 (67.7) | 8 (42.1) | 1.0 | – |
| Yes | 61 (32.3) | 11 (57.9) | 2.9 (1.1, 7.5) | – |
| CNS | ||||
| No | 139 (73.5) | 6 (31.6) | 1.0 | 1.0 |
| Yes | 50 (26.5) | 13 (68.4) | 6.0 (2.2, 16.7) | 20.9 (4.3, 100) |
| DIC | ||||
| No | 125 (66.1) | 6 (31.6) | 1.0 | – |
| Yes | 64 (33.9) | 13 (68.4) | 4.2 (1.5, 11.7) | – |
| Temperature | ||||
| < 38.5°C | 176 (93.1) | 15 (78.9) | 1.0 | 1.0 |
| ≥ 38.5°C | 13 (6.9) | 4 (21.1) | 3.6 (1.0, 12.5) | 23.2 (3.4, 158) |
| BUN | ||||
| < 6.4 mmol/L | 138 (73.0) | 9 (47.4) | 1.0 | 1.0 |
| ≥ 6.4 mmol/L | 51 (27.0) | 10 (52.6) | 3.0 (1.2, 7.8) | 9.9 (2.2, 44) |
| CKMB | ||||
| < 100 U/L | 181 (95.8) | 13 (68.4) | 1.0 | 1.0 |
| ≥ 100 U/L | 8 (4.2) | 6 (31.6) | 10.4 (3.1, 34.6) | 33.2 (5.8, 192) |
| GLU | ||||
| ≤ 6.1 mmol/L | 55 (29.1) | 10 (52.6) | 1.0 | – |
| > 6.1 mmol/L | 134 (70.9) | 9 (47.4) | 0.4 (0.1, 0.9) | – |
| LDH | ||||
| < 1000 U/L | 145 (76.7) | 10 (52.6) | 1.0 | 1.0 |
| ≥ 1000 U/L | 44 (23.3) | 9 (47.4) | 3.0 (1.1, 7.8) | 8.3 (1.9, 37) |
BUN = blood urea nitrogen; CNS = Central nervous syndrome; CKMB = creatine kinase-MB; DIC = disseminated intravascular coagulation; GLU = glucose; LDH = lactate dehydrogenase; MOF = multiple-organ failure; OR = odds ratio. Data are presented as frequency (percentage) and odds ratio (95% CIs). The adjusted variables include age-group, vomiting, diarrhea, headache, MOF, CNS, DIC, body temperature, platelet, GLU, BUN, CKMB, and LDH.