Table 1.
S. no. | Factors | Cases (n = 9) | Control (n = 36) | Odds ratio (95% CI) | P-value | |
---|---|---|---|---|---|---|
1. | Age (average = 42.5 ± 13.3 years) | ≥ Average | 4 (44.4) | 18 (50) | 0.8 (0.18–3.47) | 0.765 |
< Average | 5 (55.5) | 18 (50) | ||||
2. | Residence | Rural | 6 (66.6) | 19 (52.7) | 1.7 (0.3–8.2) | 0.456 |
Urban | 3 (33.3) | 17 (47.2) | ||||
3. | Water source | Untreated | 8 (88.8) | 27 (75) | 2.6 (0.2–24.3) | 0.384 |
Treated | 1 (11.1) | 9 (25) | ||||
4. | Anemia | Present | 7 (77.7) | 19 (52.7) | 3.1 (0.5–17.1) | 0.188 |
Absent | 2 (22.2) | 17 (47.2) | ||||
5. | Alcoholism | Present | 7 (77.7) | 25 (69.4) | 1.5 (0.2–8.6) | 0.623 |
Absent | 2 (22.2) | 11 (30.5) | ||||
6. | Common anaerobes* | Bacteroides | 0 | 3 (8.3) | 0.5 (0.02–10.6) | 0.659 |
Peptostreptococcus | 0 | 1 (2.7) | 1.2 (0.04–33) | 0.895 | ||
Prevotella | 5 (55.5) | 4 (11.1) | 10 (1.87–53.4) | 0.007† | ||
Peptococcus | 0 | 6 (16.6) | 0.24 (0.01–4.8) | 0.355 | ||
Fusobacterium | 0 | 6 (16.6) | 0.24 (0.01–4.8) | 0.355 | ||
7. | MMP-9 concentration (average = 7,878.46 pg/mL) | ≥ Average | 6 (66.6) | 9 (25) | 6.0 (1.23–29.07) | 0.026† |
< Average | 3 (33.3) | 27 (75) | ||||
8. | Matrix metalloproteinase 3 concentration (average = 21,890 pg/mL) | ≥ Average | 2 | 9 | 0.8571 (0.15–4.8991) | 0.8624 |
< Average | 7 | 27 | ||||
9. | Abscess size (average = 9.5 × 9.3) | ≥ Average | 6 (66.6) | 10 (27.7) | 5.2 (1.08–24.89) | 0.039† |
< Average | 3 (33.3) | 26 (72.2) |
Bifidobacterium and Clostridium were also screened in cases and controls; however, they were not present in any of the screened samples.
P value < 0.05 (significant).