Figure 4.
Antibody response in acute samples. N = 15 samples were evaluated for presence of both (A) anti–CHIKV-IgM and anti–CHIKV-IgG antibody or (B) IgG subtypes raised against CHIKV. The data are presented as O.D. values at 450 nm at serum dilution 1:100. These samples were used to determine (C) anti–CHIKV-IgG, -IgG1, and -IgG4 titers. (D) IgG1/IgG4 titer ratio was calculated for serum samples that were positive for both anti–CHIKV-IgG1 or -IgG4. CHIKV = chikungunya virus.
