Table 2.
GPCR | Chemical Ligand | Neurons functioning in | Behavior | Reference(s) |
---|---|---|---|---|
ODR-10 | Diacetyl (low) | AWA | Attraction | |
STR-2 | 2-Heptanone | AWCON | Attraction | (Zhang et al. 2016) |
DCAR-1 |
Dihydrocaffeic acid Benzaldehyde ? (undiluted) |
ASH | Avoidance | (Aoki et al. 2011) |
SRI-14 | Diacetyl (high) | ASH | Avoidance | (Taniguchi et al. 2014) |
SRB-6 |
Dodecanoic acid Decanoic acid? |
ASH, ADL, ADF (head)a PHA, PHB (tail) |
Avoidance | (Tran et al. 2017) |
STR-217 | DEET | ADL | “Confusant” | (Dennis et al. 2018) |
The limited number of C. elegans chemosensory GPCRs that have been paired with odorant ligands are shown.
SRB-6 rescued anterior response when expressed in these three head neurons, but promoters with more restrictive expression patterns were not used (Tran et al. 2017).