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. 2021 Mar 2;217(1):1–34. doi: 10.1093/genetics/iyaa011

Table 2.

Types of GRNs in taste hairs

Sensilla # GRNs GRN Markers Former GRN names Activators Suppressors
S-type 4
A Gr64f “Sweet” Sugars, low Na+, glycerol, fatty acids, acetic acida Bitter, Ca2+, acids
Bb Gr66a “Bitter” Bitter, high Na+, acids, polyamines, tryptophan, L-canavanine, cool temperatures
C Ppk28 “Water” H2O (hypo-osmolarity) Osmolytes, salts (e.g. Na+)
Dsc Ppk23, VGlut “Cation” High cations (e.g. Ca2+, Na+, K+)
I-type 2
A Gr64f “Sweet” Sugars, low Na+, glycerol, fatty acids, acetic acida Bitter, Ca2+, acids
B Gr66a “Bitter” Bitter, acids, cool temperatures
L-type 4
A Gr64f “Sweet” Sugars, low Na+, glycerol, acetic acida Bitter, Ca2+, acids
C Ppk28 “Water” H2O (hypo-osmolarity) Osmolytes, salts (e.g. Na+)
DL Ppk23, VGlut “Cation” High cations (e.g. Na+, K+)
E Ir94e “Low salt” Low Na+
a

A GRNs are more responsive to acetic acid in starved flies.

b

A subset of these B neurons are also positive for Ppk23 and ChAT.

c

These GRNs respond non-selectively to cations with particularly strong responses to Ca2+.