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. 2021 Jan 6;217(2):iyaa039. doi: 10.1093/genetics/iyaa039

Table 1.

Sampling-time corrected, mean pairwise (synonymous) nucleotide difference, πˇ, the estimate of mutation rate µ (per day), and the estimate of effective population size Ne for 27-year (1980–2007), 10-year (2007–2017), and 37-year (1980–2017) H3N2 data sets

27-year (1980–2007)
10-year (2007–2017)
37-year (1980–2017)
Segment μ^(×10−5) πˇ Ne^ μ^(×10−5) πˇ Ne^ μ^(×10−5) πˇ Ne^
HA 3.19 0.0318 497 1.99 0.0296 742 3.04 0.0219 361
(2.46/4.05)* (0.0225/0.0427)* (318/730)* (1.19/2.90)* (0.0241/0.0355) (502/1214) (2.38/3.77) (0.0149/0.0288) (220/533)
PB1 2.20 0.0513 1165 1.75 0.0366 1029 2.50 0.0399 798
(1.68/2.75) (0.0398/0.0635) (812/1674) (1.17/2.62) (0.0315/0.0422) (719/1606) (1.98/3.03) (0.0331/0.0471) (619/998)
PB2 1.85 0.0542 1468 1.83 0.037 1013 2.09 0.0415 993
(1.34/2.40) (0.0423/0.0663) (1030/2152) (1.16/2.54) (0.0318/0.0419) (733/1560) (1.64/2.60) (0.0348/0.0489) (770/1300)
PA 1.82 0.051 1400 1.90 0.0308 812 1.99 0.0396 995
(1.30/2.37) (0.039/0.0645) (923/2165) (1.19/2.68) (0.0255/0.0366) (582/1270) (1.54/2.49) (0.0320/0.0470) (748/1340)
NP 1.43 0.0585 2050 1.32 0.0311 1181 1.87 0.0391 1043
(0.95/1.95) (0.0444/0.0735) (1335/3297) (0.72/2.12) (0.0248/0.0381) (763/2080) (1.38/2.41) (0.0317/0.0470) (778/1430)
NA 1.84 0.0505 1372 1.71 0.0256 747 1.90 0.0332 876
(1.28/2.51) (0.0356/0.0665) (848/2087) (1.34/2.90) (0.0207/0.0312) (468/1348) (1.41/2.46) (0.0254/0.0420) (628/1220)

*Two-sided 95% confidence interval based on the distribution of estimates from 1000 bootstrap resampling.