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. 2021 Mar 31;11:635233. doi: 10.3389/fonc.2021.635233

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Copyright © 2021 Guo, Ma, Fu, Liu, Liu, Hu, Miao, Zhang, Liu, Han, You, Yang and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of proliferation capacity and drug resistance of CSCs. (A) The growth curve of A549 CSCs based on OD_490nm value on days 1, 3, 5, and 7. (B) The comparison of colony formation ability between A549 and CSCs for 14 days. (C) Viabilities of A549 cells and CSCs after treating with ADM (0, 0.1, 0.2, 0.4, 0.8, and 1.6 μM) for 24 h were determined by MTT assay. Data were expressed as mean ± SD (n = 3). *P < 0.05.