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. 2021 Mar 31;11:644840. doi: 10.3389/fonc.2021.644840

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Copyright © 2021 Yan, He, Li, Liu and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of overexpressed ITG β1 (Integrin β1) on ACSM3 up-regulated ovarian cancer cells. (A) The protein expression of Integrin β1. (B) ACSM3 up-regulated A2780 cells were transfected by ITG β1 (Integrin β1) overexpression vector and were subjected to CCK-8 assay. (C, D) Relative wound width (Scale bar represented 200 μm). (E, F) Invasion ability. Scale bar represented 100 μm. (G) Relative protein expression of p-AKT, AKT, cyclin D1, c-Myc, Vimentin, and E-cadherin. Measurement data were expressed as mean ± SD of three independent experiments. ^$$p < 0.01 versus NC; ^&p < 0.05, ^&&p < 0.01 versus Lv-Vector+NC; ^@p < 0.05, ^@@p < 0.01 versus Lv-ACSM+NC.