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. 2021 Mar 31;11:644840. doi: 10.3389/fonc.2021.644840

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Copyright © 2021 Yan, He, Li, Liu and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of ACSM3 on the growth of ovarian cancer tumor in vivo. A xenograft tumor model was built with OV-90 cells infected with Lv-shRNA1-ACSM3 or A2780 cells infected with Lv-ACSM3. (A, B) The volume of xenograft tumors. (C) The expression of ACSM3 and Integrin β1 was measured by immunohistochemistry. Scale bar represented 50 μm. (D, E) Relative protein expression of p-AKT, AKT, c-Myc, Vimentin, and E-cadherin. Measurement data were expressed as mean ± SD of six independent experiments. **p < 0.01 versus Lv-shRNA-NC; ^#p < 0.05, ^##p < 0.01 versus Lv-Vector.