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Summary of pneumococcal transmission experiments. Transmission rates of each group were compared to control group by Fisher’s exact test.
| Group | Treatment of index | Treatment of contact | Number of contacts colonized/total | Transmission rate | Fisher’s exact test compared with control group |
|---|---|---|---|---|---|
| control group | PBS | PBS | 1/14 | 7.1% | – |
| Index and contact- CSE group | CSE | CSE | 6/11 | 54.5% | p=0.021 |
| Index-CSE group | CSE | PBS | 0/8 | 0% | not significant |
| Contact-CSE group | PBS | CSE | 2/8 | 25% | not significant |
