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. 2021 Mar 31;11:623382. doi: 10.3389/fonc.2021.623382

Table 2.

Univariable and multivariable Cox proportional hazards model analysis of the prognostic value of lassoCox and three clinical factors.

Univariable analysis Multivariable analysis
HR (95% CI) p-value HR (95% CI) p-value
LassoCox: high-risk (vs low-risk) 2.00 (1.37-2.92) 3.44e-4 2.04 (1.39-3.00) 2.64e-4
Tumor stage: III+IV (vs I+II) 1.92 (1.30-2.82) 9.53e-4 1.95 (1.32-2.88) 7.73e-4
Tumor grade: G3 (vs G1+G2) 1.46 (0.98-2.17) 0.0662 1.27 (0.85-1.91) 0.248
MSI status: MSI-L+MSI-H (vs MSS) 0.89 (0.60-1.34) 0.590 0.95 (0.63-1.42) 0.800

The group in parenthesis is the reference group. HR, hazard ratio; CI, confidence interval.