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. 2021 Mar 31;11:623382. doi: 10.3389/fonc.2021.623382

Table 3.

The biological processes of the top five most frequently selected image features.

Image feature Mean coefficient Count of selection/sample size Enriched biological process for correlated genes
bMean_bin6 0.209 310/310 N/A
distMin_bin5 0.250 310/310 Cell cycle (GO:0007049)Cell cycle process (GO:0022402)Organelle fission (GO:0048285)
ratio_skewness 0.311 310/310 Muscle contraction (GO:0006936)Muscle system process (GO:0003012)Regulation of muscle contraction (GO:0006937)
major_bin10 -0.124 283/310 Muscle contraction (GO:0006936)Muscle system process (GO:0003012)Regulation of muscle contraction (GO:0006937)
distMean_bin3 0.050 268/310 N/A

Note for each round of LOOCV, features were selected independently, so some features may not be selected every time (for example, major_bin10 and distMean_bin3).