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Mutation spectrum comparison of our cohort with the 195 CRLM samples of the MSK data set (Yaeger et al. 2018). Our sequencing results were trimmed according to the standards and gene panel of the other dataset to maintain comparability. The distribution of genes and mutation were consistent between the two datasets, especially for the essential genes with high occurrences, such as TP53, KRAS, APC and PIK3CA.
