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. 2021 Apr 13;23(4):e26874. doi: 10.2196/26874

Table 1.

Reasons for vaccine hesitation fell under several Theoretical Domains Framework (TDF) constructs (left column). The rightmost column provides examples of intervention suggestions for responding to vaccine hesitancy in relation to the TDF construct.

TDF constructs Content analysis theme Example suggestions
Knowledge Lack of knowledge
  • Introduce campaigns that educate the public about using clear language in media that are commonly used to digest content (eg, social media).

Social influence Authority
  • Have nonpolitical, respected older adult Canadian celebrities take the vaccine as an example.

  • Such celebrities could be retired athletes or musicians.

Environmental context and resources Political skepticism
  • Emphasize that vaccines are rooted in science and not politics. This is a difficult quality to understand.

  • In action, this could be done by having messages come from trusted physicians instead of politicians.

Emotion and beliefs about consequences Safety
  • Highlight examples of instances when the vaccine has worked.

  • Reiterate the safety of the vaccine.

  • Reiterate the fact that the steps in the scientific development of the vaccine were not missed.