Table 1.
Baseline Demographic and Clinical Characteristics
| Total Cohort (N = 20,305) | Incident Cancer (n = 2,548) | No Cancer∗ (n = 17,757) | |
|---|---|---|---|
| Age, yrs | 50 ± 14 | 59 ± 12 | 49 ± 14 |
| Men | 9,426 (46) | 1,328 (52) | 8,098 (46) |
| SBP, mm Hg | 126 ± 19 | 132 ± 20 | 125 ± 19 |
| DBP, mm Hg | 75 ± 10 | 77 ± 10 | 75 ± 10 |
| HTN treatment | 3,097 (15) | 624 (25) | 2,473 (14) |
| BMI, kg/m2 | 26.5 ± 4.8 | 27.0 ± 4.7 | 26.4 ± 4.8 |
| DM | 839 (4) | 171 (7) | 668 (4) |
| Former smoker | 6,750 (33) | 1,035 (41) | 5,715 (32) |
| Current smoker | 5,822 (29) | 786 (31) | 5,036 (28) |
| Total cholesterol, mg/dl | 210 ± 42 | 215 ± 42 | 209 ± 42 |
| HDL, mg/dl | 52 ± 16 | 50 ± 16 | 52 ± 16 |
| Statin therapy | 820 (4) | 140 (6) | 680 (4) |
| eGFR, ml/min1/1.73 m2 | 85 ± 25 | 74 ± 21 | 87 ± 26 |
| 10-yr ASCVD risk, % | 8.2 ± 11.9 | 13.9 ± 13.5 | 7.4 ± 11.4 |
Values are mean ± SD or n (%).
ASCVD = atherosclerotic cardiovascular disease; BMI = body mass index; DBP = diastolic blood pressure; DM = diabetes mellitus; eGFR = estimated glomerular filtration rate; HDL = high-density lipoprotein; HTN = hypertension; SBP = systolic blood pressure.
∗
No cancer group included participants who died, were lost to follow-up, or had not developed cancer by the end of follow-up.