Table 2.
Specific Activities of the Human Serum Paraoxonase 1 Toward Dihydrocoumarin, Presented in Different Articles for Groups of Healthy Controls
| Reference | Title | Specific activity (DHC) [μM/min/mL] | Genotyping of subjects | |
|---|---|---|---|---|
| 1 | Alaminos-Castillo et al. (2019) | Increased PON lactonase activity in morbidly obese patients is associated with impaired lipid profile | 1.7 ± 0.5a | No |
| 2 | Bacchetti et al. (2015) | Higher levels of oxidized low-density lipoproteins in Alzheimer's disease patients: Roles for platelet activating factor acetyl hydrolase and paraoxonase-1 | 26.7 ± 4.9 | No |
| 3 | Bacchetti et al. (2019) | HDL functionality in follicular fluid in normal weight and obese women undergoing assisted reproductive treatment | 6.9 ± 0.3 | No |
| 4 | Bacchetti et al. (2020) | Plasma oxidation status and antioxidant capacity in psoriatic children | 27.2 ± 1.4 | No |
| 5 | Bains et al. (2019) | Paraoxonase 1, HDL subclasses and postsurgery acute inflammation: A pilot study | 42 ± 9a | No |
| 6 | Ferretti et al. (2012) | Lipid peroxidation and paraoxonase-1 activity in celiac disease | 68 (32–184) | No |
| 7 | Gilca et al. (2014) | A study of antioxidant activity in patients with schizophrenia taking atypical antipsychotics | 57.27 ± 1.34 | No |
| 8 | Gugliucci et al. (2014) | Paraoxonase 1 lactonase activity and distribution in the HDL subclasses in the cord blood | 60.3 ± 20.2 | No |
| 9 | Gugliucci et al. (2015) | Low protective PON1 lactonase activity in an Arab population with high rates of coronary heart disease and diabetes A | 10.4 ± 3.2 (Palestinians), 11.7 ± 3.6 (Israelis) | Yes |
| 10 | Kowalska et al. (2018) | Influence of oral contraceptives on lipid profile and paraoxonase and commonly hepatic enzymes activities | 9.2 | No |
| 11 | Lozano-Paniagua et al. (2016) | Activity and determinants of cholinesterases and paraoxonase-1 in blood of workers exposed to noncholinesterase inhibiting pesticides | 14.4 ± 0.4 | Yes |
| 12 | Marek et al. (2018) | Decreases in paraoxonase-1 activities promote a proinflammatory effect of lipids peroxidation products in nonsmoking and smoking patients with acute pancreatitis | 9a | No |
| 13 | Mogarekar and Talekar (2013) | Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B | 13.3 ± 4.1 | No |
| 14 | Murillo-González et al. (2020) | PON1 lactonase activity and its association with cardiovascular disease | 13a | Yes |
a
The numerical value was obtained from a graph.