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Age‐related transcriptional network alterations in OPCs. (a,b) GO analysis of OPC Biological Processes altered in ageing (a), from 322 core genes identified by meta‐analysis of RNA‐seq database of OPCs (b). (c) STRING analysis of the predicted interactions of OPC genes altered in ageing (PPI Enrichment p‐value <1.0e‐16); the circles represent groups of genes active along common pathways. (d) Highlighted Gpr17 node and key interactions with Cell Cycle, Synapses and ECM nodes
