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. 2021 Mar 11;12:12–24. doi: 10.18632/genesandcancer.210

Table 1. Table 1: Most significantly up- and down-regulated genes in human pancreatic ductal adenocarcinoma (PDAC) .

Top 15 up-regulated genes Top 15 down-regulated genes
Gene name Log2FC P. Value Adj. P. Val. Gene name Log2FC P. Value Adj. P. Val.
CEACAM5 3.18 2.16E-13 1.07E-10 PNLIPRP1 -3.03 2.37E-06 3.86E-05
SLC6A14 3.08 2.65E-15 3.82E-12 PNLIPRP2 -2.82 5.36E-06 7.56E-05
LAMC2 2.90 7.03E-19 1.59E-14 IAPP -2.81 2.36E-09 1.53E-07
GALNT5 2.79 3.62E-16 8.70E-13 CTRC -2.80 3.47E-06 5.30E-05
TSPAN1 2.73 2.49E-18 1.63E-14 GP2 -2.79 8.79E-06 1.12E-04
CTSE 2.68 6.00E-15 6.93E-12 CEL -2.72 1.14E-05 1.39E-04
POSTN 2.63 6.76E-13 2.53E-10 CPA2 -2.65 2.38E-05 2.47E-04
CEACAM6 2.63 1.06E-12 3.78E-10 ALB -2.63 1.43E-07 4.12E-06
ANXA10 2.36 5.23E-11 7.58E-09 FAM24B-CUZD1 -2.63 1.84E-05 2.01E-04
LAMB3 2.34 1.19E-18 1.59E-14 ERP27 -2.59 1.64E-06 2.88E-05
ITGA2 2.27 5.63E-14 4.28E-11 CLPS -2.54 1.29E-05 1.53E-04
TMPRSS4 2.26 2.85E-16 7.48E-13 SERPINI2 -2.48 1.28E-06 2.38E-05
FN1 2.21 3.25E-12 8.61E-10 PLA2G1B -2.31 2.51E-05 2.58E-04
COL11A1 2.19 3.05E-13 1.42E-10 CELA2A -2.28 1.43E-05 1.66E-04
SERPINB5 2.18 1.26E-14 1.21E-11 CELA2B -2.28 1.02E-05 1.26E-04