Table 1. Table 1: Most significantly up- and down-regulated genes in human pancreatic ductal adenocarcinoma (PDAC) .
Top 15 up-regulated genes | Top 15 down-regulated genes | ||||||
---|---|---|---|---|---|---|---|
Gene name | Log2FC | P. Value | Adj. P. Val. | Gene name | Log2FC | P. Value | Adj. P. Val. |
CEACAM5 | 3.18 | 2.16E-13 | 1.07E-10 | PNLIPRP1 | -3.03 | 2.37E-06 | 3.86E-05 |
SLC6A14 | 3.08 | 2.65E-15 | 3.82E-12 | PNLIPRP2 | -2.82 | 5.36E-06 | 7.56E-05 |
LAMC2 | 2.90 | 7.03E-19 | 1.59E-14 | IAPP | -2.81 | 2.36E-09 | 1.53E-07 |
GALNT5 | 2.79 | 3.62E-16 | 8.70E-13 | CTRC | -2.80 | 3.47E-06 | 5.30E-05 |
TSPAN1 | 2.73 | 2.49E-18 | 1.63E-14 | GP2 | -2.79 | 8.79E-06 | 1.12E-04 |
CTSE | 2.68 | 6.00E-15 | 6.93E-12 | CEL | -2.72 | 1.14E-05 | 1.39E-04 |
POSTN | 2.63 | 6.76E-13 | 2.53E-10 | CPA2 | -2.65 | 2.38E-05 | 2.47E-04 |
CEACAM6 | 2.63 | 1.06E-12 | 3.78E-10 | ALB | -2.63 | 1.43E-07 | 4.12E-06 |
ANXA10 | 2.36 | 5.23E-11 | 7.58E-09 | FAM24B-CUZD1 | -2.63 | 1.84E-05 | 2.01E-04 |
LAMB3 | 2.34 | 1.19E-18 | 1.59E-14 | ERP27 | -2.59 | 1.64E-06 | 2.88E-05 |
ITGA2 | 2.27 | 5.63E-14 | 4.28E-11 | CLPS | -2.54 | 1.29E-05 | 1.53E-04 |
TMPRSS4 | 2.26 | 2.85E-16 | 7.48E-13 | SERPINI2 | -2.48 | 1.28E-06 | 2.38E-05 |
FN1 | 2.21 | 3.25E-12 | 8.61E-10 | PLA2G1B | -2.31 | 2.51E-05 | 2.58E-04 |
COL11A1 | 2.19 | 3.05E-13 | 1.42E-10 | CELA2A | -2.28 | 1.43E-05 | 1.66E-04 |
SERPINB5 | 2.18 | 1.26E-14 | 1.21E-11 | CELA2B | -2.28 | 1.02E-05 | 1.26E-04 |