FIGURE 2.

Curcumin inhibits cell proliferation and triggers cell death in A549 and H1299 cells. The cells were treated with curcumin at different concentrations. (a) The viability of A549 and H1299 cells with various curcumin concentrations for different time. (b), (c) The proliferation of A549 and H1299 cells was detected by Ki67 staining (scale bar = 50 μm). (d) Representative cell morphological changes are shown (scale bar = 200 μm). All experiments were done more than three times independently, and all results are expressed as the mean ± SD. *P < 0.05, **P < 0.002, ***P < 0.0002, ****P < 0.0001 versus control group