FIGURE 3.

The ferroptosis‐related changes induced by curcumin in the tumor tissues of LLC‐bearing mice. (a)–(c) Contents of MDA, SOD, GSH, and iron in tumor tissue of mice. (d) Protein levels of ACSL4, SLC7A11, and GPX4 in tumor tissue lysates. (e) Immunohistochemical staining results and semi‐quantification analyses of ACSL4 and GPX4 in tumor tissues. All experiments were done more than three times independently, and all results are expressed as the mean ± SD. *P < 0.05, **P < 0.002, ***P < 0.0002, ****P < 0.0001 versus control group