Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 3;12(8):1219–1230. doi: 10.1111/1759-7714.13904

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Knockdown Beclin1 reverses ferroptosis related indicators in A549 and H1299 cells. (a) The viability of A549 and H1299 cells in siControl group, siControl+curcumin group, siBeclin1 group, and siBeclin1+curcumin group. (b) Representative cell morphological changes in each group of cells (scale bar = 200 μm). (c) The protein expression levels of P62, Beclin1, LC3, ACSL4, SLC7A11 and GPX4 in each group of cells. (d) Semi‐quantitative analysis of immunoblotting results. (e)–(g) The concentrations of MDA, SOD, GSH, and iron in each group of cells. All results are expressed as the mean ± SD. **P < 0.002, ***P < 0.0002, ****P < 0.0001 vs. siControl+curcumin group