Fig 3. An isolate from recurrent endophthalmitis with a mutation in the mismatch repair gene mutS has a higher spontaneous mutation rate compared to earlier isolates from the same patient.

Spontaneous mutation rate, measured with a rifampin mutagenicity assay, in isolates E616, E623 and E633, which were all sampled from a patient with recurrent endophthalmitis. Horizontal lines mark median values for results from 6 biological replicate experiments (each with 2–4 technical replicates).