Table 3.
Diagnostic Accuracy Indicators of the Triple Test and Colposcopy in Regard of Premalignant and Malignant Cervical Lesions
| Index | CIN 1 lesion and worse |
CIN 2 lesions and worse |
||
|---|---|---|---|---|
| Triple test (95% CI) | Colposcopy (95% CI) | Triple test (95% CI) | Colposcopy (95% CI) | |
| Sensitivity | 78.7 (74.3 - 83.2) | 80.1 (75.5 - 84.4) | 91.9 (88.9 - 94.8) | 86.5 (82.8 - 90.2) |
| Specificity | 69 (65 - 74.9) | 72.2 (67.3 - 77) | 53.6 (48.2 - 58.9) | 95.5 (93.2 - 97.7) |
| NPV | 81.1 (76.8 - 85.3) | 82.8 (78.7 - 86.8) | 98 (96.5 - 99.5) | 98.2 (96.7 - 99.6) |
| PPV | 65.68 (63.4 - 73.5) | 65.7 (60.5 - 70.8) | 20 (15.6 - 24.3) | 71.1 (66.2 - 76) |
| Diagnostic accuracy | 75 (70.3 - 79.7) | 73 (68.2 - 77.8) | 58 (52.6 - 63.3) | 94 (91.4 - 96.6) |
Abbreviations: CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value; The triple test consisted of the Pap smear, VIA, and the VILI test