Table 1. The protective effect of Mucuna pruriens on PD .

Doses used	Model of study	Effects	Ref.
5 g/kg + carbidopa	Mice	Improvement in the test of free contralateral rotation induced by 6‐OHDA compared with L-dopa	23
400 mg/kg,	Rat	Significant anti-Parkinson effect	24
2.5 or 5 g/kg/d	Rat	Restoration of endogenous neurotransmitters such as, L-dopa, dopamine, norepinephrine and serotonin content in the substantia nigra	25
2.5, 5 or 10 g/kg/d of Endocarp form of HP-200	Rat	Elevation of the dopamine concentration in brain cortex.	26
30 g	Human	Induction of marked quantity of L-dopa accompanied with the decreased duration without change of dyskinesia intensity in L-dopa response with respect to standard dose of this drug	27
15 to 40 g	Human	Symptomatic control with the 4.5% to 5.5% of L-dopa	28