Table 1. Direct protein targets of hesperetin, from DrugBank and STITCH .
Gene symbol | Protein name |
SOAT1 | Sterol O-acyltransferase 1 |
SOAT2 | Sterol O-acyltransferase 2; |
MTTP | Microsomal triglyceride transfer protein large subunit |
SHBG | Sex hormone-binding globulin |
CDK2 | Cyclin-dependent kinase 2 |
NOTCH1 | Neurogenic locus notch homolog protein 1 |
CDK4 | Cyclin-dependent kinase 4 |
PPARG | Peroxisome proliferator-activated receptor gamma |
ADIPOQ | Adiponectin |
PPARA | Peroxisome proliferator-activated receptor alpha |
DGAT1 | Diacylglycerol O-acyltransferase 1 |