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. 2021 Mar 15;13(3):e13902. doi: 10.7759/cureus.13902

Table 4. Logistic regression analysis for evaluating the risk factors for mortality in all patients with COVID-19 hospitalized in BSUH, United Kingdom.

P<0.05 was considered significant.

*Used for multivariate analysis, **compared to ≤60 years of age, ***include diabetes, asthma, COPD, heart disease, hypertension and cancer, ^HbA1c > 8.5%, ^^compared to type 1 diabetes, +diabetes excluded from risk factor (included Asthma, COPD, heart disease, hypertension and cancer), COPD: chronic obstructive pulmonary disease, BAME: Black Asian Minority Ethnicity, eGFR: estimated glomerular filtration rate, ND: not done.

  All participants Diabetes
Univariate Multivariate Univariate
p-Value OR; CI 95% p-Value OR; CI 95% p-Value OR; CI 95%
Age >60 years** <0.0001* 13.64 (4.22-44.10) 0.001 12.78 (3.01-54.22) 0.032 3.99 (1.13-14.11)
Male 0.052 1.504 (0.99-2.27) ND ND 0.342 1.44 (0.68-3.07)
Diabetes 0.392 0.92 (0.60-1.41) ND ND ND ND
Asthma 0.059 0.47 (0.21-1.03) ND ND 0.06 0.23 (0.05-1.06)
COPD 0.006* 2.18 (1.25-3.80) 0.058 1.75 (0.98-3.12) 0.18 1.84 (0.75-4.55)
Heart disease 0.037* 1.55 (1.03-2.33) 0.95 1.01 (0.65-1.58) 0.83 1.09 (0.52-2.26)
Hypertension 0.732 0.93 (0.62-1.40) ND ND 0.54 0.80 (0.38-1.67)
Cancer 0.026* 1.70 (1.07-2.71) 0.16 1.42 (0.87-2.33) 0.46 1.37 (0.60-3.20)
Risk Factors (1 or more)*** 0.273 0.91 (0.78-1.07) ND ND 0.23+ 1.45 (0.79-2.64)
eGFR <60 mL/min/1.73 m2 <0.001* 2.49 (1.678-3.73) 0.001 2.06 (1.33-3.20) 0.14 1.76 (0.84-3.72)
Hyperglycemia on presentation 0.820 0.93 (0.49-1.77) ND ND 0.54 0.77 (0.34-1.77)
BAME 0.036* 0.43 (0.20-0.95) 0.24 0.55 (0.21-1.47) 0.45 0.68 (0.25-1.84)
Type 2 diabetes^^ ND ND ND ND 0.62 0.63 (0.10-3.93)
Hyperglycemic emergencies ND ND ND ND 0.62 1.58 (0.26-9.84)
Hyperglycemia (two readings >11 mmol/L) ND ND ND ND 0.63 1.21 (0.56-2.59)
Average glucose > 11 mmol/L ND ND ND ND 0.66 1.23 (0.50-3.02)
Number of blood glucose reading per day ND ND ND ND 0.46 1.37 (0.60-3.14)
HbA1c >69^ mmol/mol ND ND ND ND 0.35 0.65 (0.26-1.59)