Table 3.
Univariate analysis for predictors of survival in stage II and III breast cancer.
| Variables | Category | n (%) | Survival at 5 years | P-value (log-rank) | HR on 5-year survival (95% CI, p-value) |
|---|---|---|---|---|---|
| Stage | Stage II | 50,189 (77.2) | 84% | <0.0001 | reference |
| Stage III | 14,798 (22.3) | 66% | 2.45 (2.36 – 2.55, <0.001) | ||
| Age | Age <65 | 43,147 (66.8) | 86% | <0.0001 | reference |
| Age 65+ | 21,570 (31.2) | 69% | 2.40 (2.31 – 2.49, <0.001) | ||
| Gender | Female | 64,415 (99.1) | 80% | <0.0001 | reference |
| Male | 572 (0.9) | 72% | 1.45 (1.22 – 1.72, <0.001) | ||
| Surgery at Primary Site | No | 1,849 (2.8) | 47% | <0.0001 | reference |
| Yes | 63,138 (97.2) | 81% | 0.26 (0.24 – 0.28, <0.001) | ||
| Chemotherapy | No | 23,749 (36.5) | 74% | <0.0001 | reference |
| Yes | 39,734 (61.2) | 83% | 0.61 (0.59 – 0.63, <0.001) | ||
| unknown | 1,486 (2.3) | 83% | 0.66 (0.58 – 0.75, <0.001) | ||
| Diabetes | No | 61,751 (95.0) | 81% | <0.0001 | reference |
| Yes | 3,236 (5.0) | 66% | 2.01 (1.89 – 2.14, <0.001) | ||
| Hypertension | No | 46,073 (70.9) | 82% | <0.0001 | reference |
| Yes | 18,914 (29.1) | 75% | 1.45 (1.39 – 1.50, <0.001) | ||
| Obese | No | 60,250 (92.7) | 80% | 0.2331 | reference |
| Yes | 4,737 (7.3) | 80% | 1.04 (0.97 – 1.12, =0.234) | ||
| Tobacco Use | No | 57,994 (89.2) | 80% | <0.0001 | reference |
| Yes | 6,993 (10.8) | 77% | 1.22 (1.15 – 1.29, <0.001) | ||
| Insurance | Private or PPO | 29,249 (45.0) | 84% | <0.0001 | reference |
| HMO | 10,999 (16.9) | 84% | 1.03 (0.97 – 1.10, =0.321) | ||
| Medicare | 15,143 (23.3) | 69% | 2.33 (2.23 – 2.44, <0.001) | ||
| Medicaid/uninsured | 7,445 (11.5) | 77% | 1.61 (1.15 – 1.71, <0.001) | ||
| Other | 2,151 (3.3) | 83% | 1.12 (1.00 – 1.25, =0.052) | ||
| Socioeconomic Status | Very Low | 7,745 (11.9) | 73% | <0.0001 | reference |
| Low | 10,140 (15.6) | 78% | 0.82 (0.77 – 0.88, <0.001) | ||
| Middle | 12,121 (18.6) | 79% | 0.75 (0.71 – 0.80, <0.001) | ||
| High | 13,455 (20.7) | 81% | 0.68 (0.64 – 0.73, <0.001) | ||
| Very High | 15,389 (23.7) | 85% | 0.53 (0.50 – 0.56, <0.001) | ||
| Missing | 6,137 (9.4) | 82% | 0.64 (0.59 – 0.70, <0.001) | ||
| Race | Non-Hispanic White | 39,211 (60.3) | 80% | <0.0001 | reference |
| Non-Hispanic Black | 4,644 (7.2) | 72% | 1.51 (1.42 – 1.61, <0.001) | ||
| Hispanic | 11,585 (17.8) | 81% | 0.94 (0.89 – 0.99, =0.012) | ||
| Asian/Pacific Islander | 7,734 (11.9) | 86% | 0.66 (0.62 – 0.71, <0.001) | ||
| Other | 1,813 (2.8) | 84% | 0.73 (0.64 – 0.83, <0.001) | ||
| Food desert | No | 61,292 (94.3) | 80% | 0.0002 | reference |
| Yes | 3,695 (5.7) | 78% | 1.15 (1.07 – 1.24, <0.001) | ||